13 EVALUTION OF THE EFFICACY OF GROWTH HORMONE TREATMENT WITH RECOMBINANT HUMAN GROWTH HORMONE (rhGH) IN “SHORT NORMAL” CHILDREN WITHOUT GH DEFICIENCY
نویسندگان
چکیده
منابع مشابه
Growth parameters and predictors of growth in short children with and without growth hormone (GH) deficiency treated with human GH: a randomized controlled study.
Seventy-seven prepubertal short children with heights below the third centile for age and gender were divided into three groups according to their peak GH response to clonidine and insulin provocation. Group (I) included 30 children with peak GH response < 7 micrograms/l, group (II) included 19 children, with GH peak response between 7 and 10 micrograms/l, and group (III) included 24 children w...
متن کاملEffect of growth hormone treatment on children with idiopathic short stature and idiopathic growth hormone deficiency
PURPOSE There are inconsistencies in the results reported in a small number of previous studies into growth hormone (GH) treatment in Korean children with idiopathic short stature (ISS) and idiopathic growth hormone deficiency (IGHD). Thus, the authors retrospectively compared the effects of GH in ISS and IGHD. METHODS From the medical records of 26 ISS and 30 IGHD children, auxological and b...
متن کاملNo Improvement of Adult Height in Non-growth Hormone (GH) Deficient Short Children with GH Treatment
It is still in doubt whether the standard-dose growth hormone (GH) used in Japan (0.5 IU/kg/week, 0.167 mg/kg/week) for growth hormone deficiency is effective for achieving significant adult height improvement in non-growth hormone deficient (non-GHD) short children. We compared the growth of GH-treated non-GHD short children with that of untreated short children to examine the effect of standa...
متن کاملRelationship between initial treatment effect of recombinant human growth hormone and exon 3 polymorphism of growth hormone receptor in Chinese children with growth hormone deficiency.
The aim of this study is to investigate the frequency distribution of exon 3 deleted (d3-GHR) genetic polymorphism of growth hormone receptor (GHR) in growth hormone deficient (GHD) Chinese children and to explore the correlation between the growth promoting effects of recombinant human growth hormone (rhGH) and exon 3 genetic polymorphism of GHR in GHD children. In this study, 111 GHD (exclude...
متن کاملPsychological response to growth hormone treatment in short normal children.
This study provides a controlled assessment of the psychological (and physical) effects of growth hormone treatment. Fifteen short 'normal' children (height SD score < -2) have been treated with growth hormone since the age of 7/8 years. They, together with untreated short controls and average controls (10th-90th centiles), were assessed at recruitment, after three years, and after five years. ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1992
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199208000-00036